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Symptoms of PBC. PBC does not always cause symptoms, but some people may experience: bone and joint aches; fatigue (extreme tiredness) itchy skin; ... Bile is a liquid produced inside。

When bile can’t flow properly through your biliary system, it affects all of these organs and vessels. Bile backs up in your bile ducts and organs, irritating the tissues and interfering with。

When there’s a hole in any part of the bile duct, it can leak bile. This can occur during some procedures or due to injury. See more

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